Treatment for neuroblastoma is determined by the child’s assigned risk group. Treatment for low or intermediate risk neuroblastoma is very different from treatment for high-risk neuroblastoma. Treatment for high-risk neuroblastoma includes multiple cycles of chemotherapy, surgery to remove the tumor, autologous stem cell transplant(s) (infusion of child’s own stem cells after very strong chemotherapy), radiation, and antibody therapy with Unituxin.
Multiple rounds of high-dose chemotherapy
Surgery to remove primary tumor
Autologous stem cell transplant(s) (infusion of child’s own stem cells after very strong chemotherapy)
Antibody therapy with Unituxin, GM-CSF, IL-2, and isotretinoin (also known as retinoic acid)
GM-CSF=granulocyte-macrophage colony-stimulating factor; IL-2=interleukin-2.